is
an Australian company, specialising in the development of monoclonal antibody
therapies for multiple myeloma and other blood cancers. Multiple myeloma
is a fatal blood cancer that affects more than 100,000 patients worldwide.
IST has considerable expertise in the genetic engineering of monoclonal
antibodies based on more than ten years of research conducted at the University
of Technology, Sydney.
IST's lead antibody therapy is designed to target specifically and kill
multiple myeloma cells. It does not target healthy cells, which means
there should be few side effects. If successful, it would have significant
advantages over existing cancer treatments, resulting in extended and
improved quality of life for sufferers.
There are two types of multiple myeloma. IST's lead product for the treatment
of the most common type of multiple myeloma is in the late pre-clinical
phase of development. IST has also commenced development of an antibody
designed to treat patients with a less common type of multiple myeloma,
and is evaluating the effect of its monoclonal antibodies on other lymphoproliferative
disorders.
IST has a strong management team,
with a proven track record of commercialising technology, and a talented
drug development group that has significantly advanced the development
of its lead therapeutic.
"...the latest generation
of Mabs represents the biggest growth area in biotech today."
DNA The Secret of Life, p.126
James D Watson, 2003
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